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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

因为一种鲜为人知的病毒所造成的重大影响,2016年将在全球卫生方面被人们铭记。这似曾相识,不过此次登上全球头条新闻的不是埃博拉病毒,而是寨卡——一种通过蚊子传播的病毒,大脑存在缺陷的新生儿数量在巴西急剧增加与此有关。
日立数据系统:提升士气的狗狗节

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

[k?n'gr?tju.leit]
Many technicians think that during the course of this century computerized robots might compete and win against humans.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

But her success doesn't come cheap and her mother has already spent £5,000 on elaborate dresses and entry fees.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

n. 制作人,经理人,主办者

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

感情破裂搜索排行居首的是贾斯汀?比伯和赛琳娜?戈麦斯分手的消息,此外维多利亚?彭德尔顿打败了乔治亚?索帕,成为搜索次数最多的真人秀选手。
Do you often feel gloomy and down in the dumps?
The general weakness in the renminbi, which fell 1.3 per cent in January and had weakened by 2.2 per cent in the final quarter of 2015, is likely playing a part, by making overseas goods more expensive. However, exports have yet to receive a boost from the currency’s depreciation.
如果你对某个内容不懂,就可以立即提问。如果你坐在前排,并和老师有眼神交流,你的老师就很可能从你的面部表情就能得知,你对某个内容不太明白。你需要举起你的手,表示你有疑问。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

[kru:]
你永远都不能把一只狼变成宠物狗。
单词polish 联想记忆:
Get ready to see ads from the neighborhood pub on Twitter

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 楼市冰火两重天 下一步何去何从
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

金维刚表示:“2016年居民消费价格指数仅同比上涨2%,低于预期的预测指标。属于温和通胀范围,反映了物价水平得到有效控制并保持基本平稳。”

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

An escalating war on drugs in the Philippines has led to almost 1,800 deaths under new president Rodrigo Duterte, the country’s police chief has said.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

10月份,日本生产增长速度突然提升,让决策者对日本经济的实力有了更多希望,或许也可以理解为释放了更多喜忧参半的信号。
3The United Kingdom

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
From the themed collection: 净水器行业大家居之路或可取
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

今年中国经济成V字形强劲复苏,随之而来的是许多关于城市房价疯涨的报道。
v. 改革,改造,革新

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Entrepreneur Pat Crowley, the hydrologist who invented the Chapul cricket protein bar, used Bigcommerce to validate early interest in his products and build the momentum to negotiate deals with health food stores and supermarkets. The team recently recommitted toBigcommerce, despite a compelling opportunity to switch to the Shopify platform for far less money. “We don’t think we will outgrow them anytime soon,” he said.
卡利南和瑞兹各提一只装着所有奖项结果信封的手提箱——也就是说,每个奖项都有两只信封。

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 家居产品深陷环保质量漩涡
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

But Schultz didn't stop there. The chief executive also offered free coffee for a few days during the shutdown to customers who bought someone else their drink. Schultz hoped the campaign would help people "connect with one another, even as we wait for our elected officials to do the same for our country."
“治理空气,现在办法是有的,关键是看下多大决心。”
ec出,centri中心一出中心一古怪的;离心的
2015年最需要迎头赶上的品牌:由于产品线陈旧,大众今年的销量下降了11%,影响了费迪南德o皮切的“称霸全球”计划。沃尔沃的销量则下跌了17%,自从被中国车企收购后,该公司至今还没有任何进步。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

财新经济学家何帆表示:“这表明宏观经济已进一步趋稳,经济结构正在改善。今后必须协调财政政策和货币政策,尽可能避免大规模刺激。”

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

支持:影片可能会凭借出色的票房表现从缓慢变革的奥斯卡投票人群上获益。
"It is very reassuring to learn that the government of China has set a target of 7.5 percent GDP growth while trying to keep inflation at a manageable level. It will not only maintain China's prosperity, but also help spur the regional and global economy, which Indonesia can benefit from."

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

戴维皮林(David Pilling)

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

胡润估计,如果此举获得成功,王健林的净财富可能会猛增至逾500亿美元,令他跻身世界前十大富豪之列。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

夏季期间,中国股市泡沫破裂,数万亿美元的市值因而蒸发。尽管政府作了大量努力遏制股市暴跌,上海证券综合指数仍由7月12日的峰值一路下滑,到8月26日时下跌了43%。
确实有人有近乎完美的记性,可以从过去经历中检索出大量信息。只是,即使很多人认为这样的记忆已经很完美,他们有的时候也不能准确清晰地记起一些特定的细节。虽然真正完美的记忆并不存在,但你还是可以拥有近乎完美的记忆力,超越这些记忆达人,去抵抗岁月给你带来的疾病和健忘。
由西班牙IQS商学院、台湾辅仁大学(Fu Jen Catholic University)和旧金山大学(University of San Francisco)三家合办的管理学硕士项目排名升幅最大。其全球创业管理硕士项目的排名上升34位,至第43位,逆转了去年下滑19名的势头。这是唯一一个在三大洲授课的项目,其在国际课程体验方面排名第一。
节目40 歌曲《难忘今宵》李谷一 张英席 白丽莎(孔子学院学员)、茹丝(孔子学院学员)、李天翼(孔子学院学员)、吴孟天(在华留学生)

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

Consider this: Will the experience enhance your knowledge and play to your strengths? Will it introduce you to new concepts and new people? (All great reasons to say yes!) Will it require you to develop new techniques for managing your team or working with more experienced people? Embrace this challenge and get out of your comfort zone.
“We are currently investigating how this could have happened, and deeply regret that this occurred,” PwC said. “We appreciate the grace with which the nominees, the Academy, ABC, and Jimmy Kimmel handled the situation.”
美国各地许多餐馆和商店星期三向美国退伍军人提供免费服务或优惠,以纪念一年一度的退伍军人节。
An increasing amount of clients are non-Koreans, from China, Japan, the Middle East and even Africa, and ministers believe medical tourism will help boost the Korean economy.
"As robotics is expanding into nearly every industry, Chinese robot makers should realize the gap between them and foreign brands, take advantage of China's robotics development boom and learn from foreign experience to help China grow from the world's largest robot market into a robot manufacturing power," said Qu.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

2. 麦嘉华对贝南克灾难性QE计划的末日警告
2017年,衡量工业品出厂价格、反映经济活力的主要指标--生产者物价指数(PPI)上涨6.3%,结束了自2012年以来的连续下降态势。2016年PPI下降1.4%。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

Rouslan Krechetnikov和Hans Mayer对液体的溅出现象进行了研究。他们考察的课题是:人们在端着咖啡杯走动时咖啡的溅出情况,给你个提示吧,在你走到第七步至第十步之间,咖啡最容易溅出。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

清华大学位列第45名,是亚洲排名第三的高校。北京大学位居第57位。浙江大学排名第67位,本次是该校首次跻身该榜单100强。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

2.《洛奇》
5. 范冰冰 1700万美元
The regulator said that “faced with a complex and volatile market environment,” funds had realised gains of only Rmb294.5bn in the first half, a drop of 42.3 per cent.
3. Enlisted military personnel

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

2014年最佳引擎榜单的其他入选者还包括宝马5系豪华轿车和紧凑型雪佛兰科鲁兹(Cruze)所使用的涡轮增压柴油发动机,保时捷Cayman双座运动跑车的水平对置2.7升6缸发动机以及大众汽车捷达紧凑车的1.8升4缸涡轮增压发动机。
AFI Movies of the Year
Many bosses hold their staff accountable, but the best show that they hold themselves accountable as well. This means adhering to the same guidelines they set for their employees and taking responsibility for both team successes and failures。
8.Yes Man

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

JM Family Enterprises
中国官方采购经理人指数(PMI)显示,中国制造业活动出现了3月份以来的最慢扩张速度。与此同时,汇丰银行(HSBC)发布的正式PMI指数也出现了6个月内的最低读数。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

这些专家都不是轻量级的。杰出的历史学家玛格丽特?麦克米伦(Margaret MacMillan)在2013年12月的一篇为布鲁金斯学会(Brookings)撰写的文章中说:“像1914年的世界一样,我们正在经历国际权力结构的转换,新兴大国正在挑战老牌大国。”她补充说,“如今,同样的一幕正发生在美国与中国,以及中国与日本之间”,同时她还表示,“中国与它另外两个邻国——越南和马来西亚——也有爆发冲突的可能性。”
These countries performed the best overall in the 2017 Best Countries rankings. The rankings aim to gauge global perceptions of the world’s biggest economies.
But 'averages' are old data, not future facts. Happy talk won't restart a bull. And more warnings won't puncture an old bubble. Cycles have lives of their own, move up and down when they damn well feel like it. That's nature.
Paris (AFP) - Some 1,400 people living in France have either joined the jihadist cause in Syria and Iraq or are planning to do so, Prime Minister Manuel Valls said Monday.
根据乔治亚工学院2014年的一项研究,运动确实可以开发智力,即使你不喜欢举重训练或者不喜欢健身馆的环境,想改用吃坚果的方式提高记忆力,通过锻炼提高记忆力其实只需要20分钟。在这项实验中,研究人员要求参与者进行20分钟的高强度训练,他们发现,仅仅20分钟就可以让年轻人的“事件记忆”能力(也叫长期记忆力)提高10%。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
From the themed collection: 48%居民预期下季房价不变
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

But with the US close to full employment and inflation moving up towards the target, “you can see how tighter policy would be warranted,” he says. “It wouldn’t take a whole lot to shift the equation.”
《财富》美国500强公司苹果(Apple))已宣布,将从现金中拿出300亿美元用于股票回购。这个消息让投资者很高兴:股价暴涨,甚至在消息发布一周后,这只股票相对于标准普尔指数在这7天上涨了12%。苹果有一项规模更大、总额高达1300亿美元的资本回报计划,将一直延续到2015年,而这些回购就是这项计划的一部分。
This has given “edtech” start-ups, such as Silicon Valley-based Coursera and London-based FutureLearn, a foothold in the market. Expect them to continue this year, perhaps with a merger with a bricks-and-mortar higher education establishment.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

专家警告说,在普通词汇中添加数字或符号根本没用。斯莱恩说:“黑客们都知道你的小伎俩,对容易破解的密码稍作调整不会更安全。”
A New Year greeting to cheer you from your daughters.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 雷士照明要做全球前三的企业
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

其他入围者分别是:《失去信号:黑莓离奇崛起与惊人陨落背后不为人知的故事》(Losing the Signal: The Untold Story Behind the Extraordinary Rise and Spectacular Fall of Blackberry),作者杰基麦克尼什(Jacquie Mcnish)和肖恩缠尔科夫(Sean Silcoff)回顾了黑莓是怎样偏离了航向;《数字黄金:比特币背后不为人知的故事》(Digital Gold: The Untold Story of Bitcoin),作者纳塔涅尔波佩尔(Nathaniel Popper)审视了虚拟货币比特币的崛起;《音乐如何变免费:一整代人犯下同样罪行的后果》(How Music Got Free: What Happens When an Entire Generation Commits the Same Crime?),作者斯蒂芬威特(Stephen Witt)介绍了盗版和对等网络共享(P2P)扰乱唱片业的历史;《做不完的事:女人、男人、工作、家庭》(Un滻椀猀栀攀搀 Business: Women Men Work Family),作者安妮-玛丽斯劳特(Anne-Marie Slaughter)在书中讨论了实现性别平衡面临的挑战,以及《行为不端:解读行为经济学》(Misbehaving: The Making of Behavioural Economics),作者理查德泰勒(Richard Thaler)追踪了行为经济学的发展。
The last leg of the year is set to be a busy one for initial public offerings on both sides of the Atlantic, with companies including Italy’s Pirelli, Alibaba-backed Best Logistics and video streaming platform Roku lining up to list.
Frederickson说:“人们远离职场越久,他们想要再次踏入就越难。”

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

port部分+ion→一部分→部分,一般
The 62 universities account for 12.4% of the list. The only country with a larger number of universities listed is the US, which accounts for 27.8%.
vt. 谣传

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

Emma Morano’s singular achievement in life may have been perseverance. She lived for 117 years, crediting her longevity to raw eggs and her lack of a husband. She died on April 15.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

They also arrived 40 minutes late for the official welcome and were running late to an event in Vancouver, too.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

pilot
“失业”是金融类最热门的搜索项,其次是“华尔街公司”和“产品召回”。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

科派斯塔克表示,东京回归榜首并不让人惊讶,因为东京的高工资推动了物价的上涨,房价和房租也很昂贵。
福布斯表示,如果不扣除管理费和税费,在2015年6月1日到2016年6月1日期间,全球收入最高的10位女星共入账2.05亿美元。
201103/129769.shtmlEveryone tells a white lie on occasion, it’s just a question of why. Some white lies save relationships, some ease a hectic situation, and others buy us time. We all do it, so there is no reason to deny it. As long as we aren’t hurting others or breaking the law, these innocent lies can make life more pleasant. Most of these white lies only stretch aninterpretation of what the truth actually is anyways. Here’s a list of the 10most common white lies and why we tell them.
银行、基金公司和保险公司从内地涌向香港,收购这里的高端写字楼,导致香港政府宣布将释放更多土地,在火爆的城市中心地段进行商业再开发。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

拥抱世界
苹果(Apple)正面临着市值跳水的窘境,苹果股价从去年9月至今已下跌了35%。众多卖方分析师纷纷献计献策,现在甚至有人建议苹果推出廉价iPhone。摩根士丹利(Morgan Stanley)公司的凯蒂?休伯蒂对中国这一全球最大的智能手机市场进行了分析,并给大家算了一笔账。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 东莞治理工业“二房东”
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

['greisf?l]
他说,杂志和作者在这起最近发生的丑闻中都有不可推卸的责任,声明中还说,《肿瘤生物学》在2015年就已经因同行评议过程存在类似问题而撤销一些论文。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

If you plan to visit Brazil for the Olympic games, and to focus on sport and having fun, Google has you covered. In anticipation of the 2016 Rio Olympics, the search giant is bringing the 'Explore' feature to Brazil Maps.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

汤姆?汉考克(Tom Hancock)上海补充报道
18. Most Interesting Apology (tie) On Nov. 18, The Hollywood Reporter disgorged a 1,200-plus word apology for not including any nonwhite performer in its Oscar actress round table. Soon after, the director Alex Proyas and Lionsgate apologized for the lack of diversity in the cast in their new movie “Gods of Egypt.”
The latest commerce ministry figures do not include real estate purchases by individuals, many of whom exploit loopholes in China's capital control regime to obtain foreign currency. But the foreign exchange regulator has recently moved to close such loopholes, notably by tightening control of forex purchases by individuals, who are allowed to exchange $50,000 worth of renminbi for foreign currency each year.
泡沫气球是泡泡和气球的混合体。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

以下是今年BrandZ全球最具价值品牌百强榜出现的一些趋势:
昨天,中国一次控制爆破让19栋楼在10秒钟之内被夷平。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

有了正确的工具,你就会发现自己的工作生活变得更加高效。(财富中文网)
Skyfall Bond girl Berenice Marlohe has joined the all-star cast of Terrence Malick’s latest movie, which is in production in Austin.
New investment in Europe was up 28 per cent on the $18bn registered in 2014, a smaller increase than 2014’s doubling of the 2013 figure. Investment in the US was up 17 per cent compared on 2014’s level of $12.8bn.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

1. Wal-Mart Stores
全国居民人均可支配收入实际增长6.3%;
If you are working your butt off and not getting paid enough to pay your bills, you might be overqualified and underpaid for your position. Go find a job that pays what you deserve.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

The base hopes to keep up public awareness of pandas and the necessity of conservation of their natural habitats while Increasing the wild population by reintroducing individuals into areas in China where populations have declined.
10.Fears of Another Tsunami

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
From the themed collection: 房产经纪人私收客户50万消失
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
From the themed collection: 盘点2015家居市场十大“新常态”
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

Total growth in new orders softened as new export orders rose at about the same pace as a month prior. But job shedding quickened, while input price growth edged lower and prices charged to clients picked up slightly.
Cheng further says, "once you find a list that fits your needs, just tap on the list to see suggested locations. Then swipe right or left to see more options and tap 'read more' or the arrow at the bottom of the screen to select a venue and get more details.".
然而,在毕业3年后,担任部门负责人或以上级别职位的女性(59%)显著少于男性(68%)。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

顺便说一句,伦敦的自行车租赁制度再简单不过了:走到任何一个租车点,刷卡付费就可以带走一辆自行车。当你使用完毕时,把车丢在附近的河里就行。这些自行车都是一次性的!
坚持依法全面履职。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 深圳加快建立多主体住房供应体系
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

年龄:50岁
圣文森特(St. Vincent),《数码证人》(Digital Witness), Loma Vista/Republic
Last year, quality supervision authorities across China handled 36,000 cases relating to violations of laws on quality standards, involving 2.3 billion yuan's ($333 million) worth of goods, Han said.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

为了解决上述问题,报告建议应尽快制定电子商务法。同时,该报告还呼吁应建立一个在线信用体系,以此加强对电子商务行业的纪律监督。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Type A and Type B personality theory describes Type A individuals as outgoing, ambitious, rigidly organized, highly status-conscious, sensitive, impatient, anxious, proactive, and concerned with time management.
我的核心价值观是什么?作为一个人,对你来说什么是重要的?家庭、健康、信仰、工作还是其他?确保在你的生活中,你追寻了自己最在乎的东西。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Jumping all in is rarely ever successful. There are success stories about people who invested everything once and came out winners after six months or a couple years, but those are rare. Risk management is an essential factor in any startup, and balance is vital. You can absorb losses more easily if you take smaller risks in the beginning. Those will provide essential and productive lessons.
The Turkish president said Angela Merkel, the German chancellor, was “no different from the Netherlands” and urged émigré Turks not to vote for “the government and the racists” in upcoming European elections. Ms Merkel faces a tough re-election bid in September.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

源于:strike(v 打击;军事进攻;铸造;敲钟;罢工)
人们大多认为,中国的智能手机只会越来越便宜。与此相反,她援引一些研究结果,表明去年中国智能手机的平均售价趋于稳定。同时随着中国用户开始购买品质更好的智能手机,售价实际上已开始走高。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
From the themed collection: 屡挫屡战 欧普照明IPO再上会
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

2010年我们是否还会经历另一场“甲流”?
John Authers

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

据中央电视台报道,她的妈妈在1月30日才发现了此事。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

em进入,brace胳膊-拥抱
5、毕福剑违纪
利拉詹纳
9. The brain literally starts eating itself when it doesn't get enough sleep. Chronic sleep deprivation causes the 'clearing' process that usually happens when we sleep to kick into hyperdrive, prompting the brain to clear a huge amount of neurons and synaptic connections away.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

有抱负的年轻领导人已经更注重利用自己的影响力,而不是试图凭借其职位或头衔所带来的权威来发号施令。很多人已经拥有了领导经验——不是通过在老牌机构中的晋升,而是通过领导自下而上的运动和志愿组织、或是打造自己的初创公司。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

通用汽车公司(General Motors)帮助改善了大峡谷州的就业前景。今年3月,这家汽车制造商宣布,计划在凤凰城郊区钱德勒建设该公司的第四座信息技术创新中心。通用汽车预计将雇佣1,000名员工,主要包括为这座新中心效力的软件开发人员、数据库管理员和系统分析师。通用汽车公司首席信息官兰迪?莫特(Randy Mott)在新闻稿中宣布了这个举措,他表示,“大凤凰城地区是出色的枢纽,吸引了新兴技术人才——从大学毕业生到职场专业人士。”
Ahead of the release, economists at ANZ said they expected inflation to pick up in January owing to rising food prices, and the low commodity prices would weigh on the CPI.
“I thought it would be impossible to replace Steve, and to some extent that’s true,” says Professor Michael Cusumano of MIT’s Sloan School of Management. “But internally the spirit is still alive and the company is organising around a less confrontational culture. We have to give Tim credit for that.”

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

As the stars' private jets swooped in, the internet was going mad for 'the Dad bod'; the slightly flabby male physique was trending and there were plenty of examples on screen. Deborah Cole of AFP noted a “sweating, panting and shirtless” Gerard Depardieu in Valley of Love and a flash of Joaquin Phoenix's “tubby tummy” in Woody Allen's Irrational Man. When Colin Farrell strode the red carpet for the premiere of The Lobster, he looked his usual trim self – but in the film he is distinctly paunchy. To add some girth for the role of a lonely singleton in Yorgos Lanthimos' absurdist black comedy, Farrell went on a massively calorific diet that included drinking melted ice cream, he told the Hollywood Reporter. Eating “two cheeseburgers, fries and Coca-Colas, and two slices of chocolate cake at 10am is not that fun,” he said. “And I love cheese?burgers."
智能烤箱

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

凯莉·克莱森、蒂姆·麦格罗、泰勒·斯威夫特、凯莉·安德伍德、米兰达·兰伯特等人的现场表演high翻了米高梅大花园露天剧场。
8.俄罗斯

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Zhang Guoli to host 2014 Spring Festival Gala

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

许多管理者提到了一些极其失礼的情况。求职者:
The US electoral college has failed doubly.
课程安排:伊利诺州埃文斯顿校区授课时间为每隔一周的周五至周日;佛罗里达州迈阿密校区每月上一次课,授课时间为周四下午至周日中午

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

The UK’s Warwick Business School recorded the best progression at the top, moving up from 16th to ninth place, while the Shanghai Advanced Institute of Finance (Saif), based at JiaoTong University, enjoys the bestprogression overall, jumping from 28th to 14th place.
希萨柯既是一位不可或缺的政治导演,也是当代电影中的伟大诗人之一。他为北部马里圣战者管辖之下的生活所绘的图像既残酷又惊人,但也温柔、慷慨儿惊人的有趣。希萨柯并没有把暴力极端分子人性化,而是展示出,他们已经成了这种人,也反映出我们身上普遍的、悲剧的天性。但他的影片还坚持认为,反对狂热主义,唯一有效而且道德的方式就是人道主义。他以反讽而正直的方式言说了这一观点,或许最重要的是,以艺术的方式言说了这一观点。
3The United Kingdom
推进国际贸易和投资自由化便利化。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

与IBM合作,将iPad和iPhone销售给大企业客户,只是苹果在库克领导下打破自身藩篱的一个例子,而这是乔布斯一直不愿做的。
如果你是一个工薪阶层的白人,担心这个充满国际性的新世界会摧毁或贬抑你所珍视的身份认同,那么你并没有一种在文化上能够被接受的方式,去阐明自己内心感受到的危机。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

Three of former US president Barack Obama's tweets were among Twitter's list of 10 most retweeted this year, while none of current US President Donald Trump's tweets made the list.
值得庆幸的是,这些户籍规定正在发生改变。12月初,在中国中央经济工作会议上,与会代表建议给予农村居民城市户口,这也强有力地证明了户籍制度正在变化。温家宝总理于12月底呼吁,应加快户籍制度改革的进程。
这家总部位于亚特兰大的集团预测,经并购、资产剥离和汇率波动调整,今年销售额将增长3%,而之前的预期为4%至5%。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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The most exciting part is the offseason
Ms Rogers added that she had not given her son parental consent to play the game as stated in its terms and conditions, and that as the game was free to play, the studio could not claim loss of profit as a result of the cheats.

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